Last update
3/21/2026

Overview

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 9 Reviews
8.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Iron (from Ionic Plant Based Minerals)
2 mg
10%
HSO Probiotic Blend (5 Billion CFU)¹Saccharomyces boulardii, Organic Barley Grass², Organic Oat Grass², Lactobacillus plantarum, Bacillus subtilis, Bifidobacterium lactis, Bifidobacterium bifidum, Lactobacillus rhamnosus, Bifidobacterium breve, Lactobacillus casei, Lactobacillus salivarius, Lactobacillus acidophilus, Lactobacillus brevis, Bifidobacterium longum, Lactobacillus paracasei
410 mg
+
Ionic Plant Based Minerals
290 mg
+
📅 Last updated:

Most Useful Reviews

9
Helps manage pain
231 people found this helpful
I learnt about the benefits of probiotics for conditions like Crohn's disease from my cousin. Probiotics help control inflammation and improve digestive health. After starting on Primal Defense Ultra, my abdominal distention decreased, and I no longer experienced daily abdominal pain, joint pain, or flare-ups for the first time in 20 years. This product has been invaluable for managing my Crohn’s disease and arthritis. I highly recommend it for similar conditions.
Read More
10
Life-saving probiotic
8 people found this helpful
This probiotic has truly transformed my life. For ten years, I struggled with IBS-D, often unable to venture far from home. I felt like a prisoner bound to the bathroom, and nothing seemed to provide complete relief. During a visit to a health food shop, a staff member recommended Primal Defense, which required no refrigeration. I bought it four years ago, and I've never felt better since. After running out during the pandemic and trying another product, my IBS-D flared up again. It became evident that I need Primal Defense for my wellbeing, and I was thrilled to find it on iHerb at a lower price. I can’t express enough how much this probiotic has saved my life.
Read More
9
Pain reduction
2 people found this helpful
So far, so good! After being diagnosed with H. Pylori, I researched ways to heal my gut. I underwent triple antibiotic therapy, followed by Mastic Gum and probiotics. After about two weeks, I began with one capsule per day, but increased it to two due to lingering stomach pain. I’m pleased to say the pain is now virtually non-existent. Thank you, iHerb, for this great product and excellent service!
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Helps manage pain
231 people found this helpful
I learnt about the benefits of probiotics for conditions like Crohn's disease from my cousin. Probiotics help control inflammation and improve digestive health. After starting on Primal Defense Ultra, my abdominal distention decreased, and I no longer experienced daily abdominal pain, joint pain, or flare-ups for the first time in 20 years. This product has been invaluable for managing my Crohn’s disease and arthritis. I highly recommend it for similar conditions.
Read More
10
Life-saving probiotic
8 people found this helpful
This probiotic has truly transformed my life. For ten years, I struggled with IBS-D, often unable to venture far from home. I felt like a prisoner bound to the bathroom, and nothing seemed to provide complete relief. During a visit to a health food shop, a staff member recommended Primal Defense, which required no refrigeration. I bought it four years ago, and I've never felt better since. After running out during the pandemic and trying another product, my IBS-D flared up again. It became evident that I need Primal Defense for my wellbeing, and I was thrilled to find it on iHerb at a lower price. I can’t express enough how much this probiotic has saved my life.
Read More
9
Pain reduction
2 people found this helpful
So far, so good! After being diagnosed with H. Pylori, I researched ways to heal my gut. I underwent triple antibiotic therapy, followed by Mastic Gum and probiotics. After about two weeks, I began with one capsule per day, but increased it to two due to lingering stomach pain. I’m pleased to say the pain is now virtually non-existent. Thank you, iHerb, for this great product and excellent service!
Read More
7.5
Improved digestion experience
22 people found this helpful
Works for me! Starting in December 2010, I had persistent stomach issues that affected my appetite and digestion. After taking these consistently, I noticed a significant improvement. My appetite and digestion returned to normal, and I stopped having painful gas after eating. I'm ordering another bottle and plan to take these indefinitely.
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0
Quality control concerns
9 people found this helpful
BEWARE of some of their products. In spring 2016, this company had a serious salmonella issue with their Garden of Life Raw Meal product. I used to use this product regularly but suffered serious food poisoning as a result. After unknowingly re-infecting myself, I felt extremely weak and lost 22lbs. When I contacted the company post-recovery, they were unhelpful regarding my medical concerns. Take caution with their products due to quality control issues and lack of support.
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Frequently Asked Questions

9
Pain reduction
2 people found this helpful
So far, so good! After being diagnosed with H. Pylori, I researched ways to heal my gut. I underwent triple antibiotic therapy, followed by Mastic Gum and probiotics. After about two weeks, I began with one capsule per day, but increased it to two due to lingering stomach pain. I’m pleased to say the pain is now virtually non-existent. Thank you, iHerb, for this great product and excellent service!
7.5
Constipation relief
4 people found this helpful
An excellent supplement! I was diagnosed with an obstruction between my large and small intestines, causing constant constipation. Traditional treatments didn’t help. After a month of taking this supplement I experienced bloating initially, but that subsided, and the pain in my intestines has diminished significantly. I no longer suffer from constipation.
2
No relief
I hoped this would help alleviate my digestive troubles, including constant hunger and stomach pain. However, it did not provide the relief I was looking for.
10
Life-saving probiotic
8 people found this helpful
This probiotic has truly transformed my life. For ten years, I struggled with IBS-D, often unable to venture far from home. I felt like a prisoner bound to the bathroom, and nothing seemed to provide complete relief. During a visit to a health food shop, a staff member recommended Primal Defense, which required no refrigeration. I bought it four years ago, and I've never felt better since. After running out during the pandemic and trying another product, my IBS-D flared up again. It became evident that I need Primal Defense for my wellbeing, and I was thrilled to find it on iHerb at a lower price. I can’t express enough how much this probiotic has saved my life.
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